La Medusa was opened by Sherri Serino and Lisa Becklund in October 1997. The two developed a "Sicilian Soul Food" menu inspired by the recipes of Sherri's Sicilian grandmother. The name La Medusa came from Sherri's mentor, Claudia Medusa.Current chef and co-owner, Julie Andres, worked closely with Serino, learning the history and traditions of Sicilian food. In 2001 Julie traveled to Sicily to immerse herself, experiencing these traditions first-hand.