By far the majority of venous disease is secondary to venous insufficiency which is caused by reflux of the superficial leg veins. What is superficial venous reflux? Superficial veins are those veins located just beneath the skin. The longest of these superficial veins is the greater saphenous vein. It begins that the ankle and runs up the inside part of the leg and then at the groin connects to a the main deep vein of the lower extremity, the femoral vein.
